This is a literature review of how cannabinoids work, current drug development,
and current clinical research on the use of cannabinoids for pain relief. The
researchers include studies of cannabinoids for pain treatment regardless of
pain type or cause. Studies or reviews using animal models of pain are also
included. Articles relating to the physiology and pharmacology are evaluated.
There is an increase in cannabinoid drug development. Newer agents have fewer
adverse effects and include recently developed cannabis medicinal extracts for
sublingual use (approved in Canada). These show promise of pain relief in initial
clinical trials. Several synthetic cannabinoids have also been studied in humans,
including two that are available on the international market. The investigators
conclude that cannabinoids provide a novel approach to pain management and are
a potential addition to available treatment options. Burns TL, Ineck JR. Adapted
from Ann Pharmacother. 2006 Feb;40(2):251-60.
Read more: PMID 16449552
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
Credit: PubMed, developed by the National Center for Biotechnology Information
(NCBI) at the
National Library of Medicine (NLM).
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