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Managing Risks

Responding to Problematic Drug-Related Behavior

If problematic drug-related behavior is identified during long-term opioid therapy, the clinician must decide among several actions:

  • revise the structure for prescribing and continue opioid treatment,
  • continue treating pain without opioids, or
  • discharge the patient from the practice.
In the United States, opioid therapy cannot be continued if the clinician believes that the patient has engaged in diversion of a controlled prescription drug to the illicit market. This is uncommon. More often, the decision must be made in response to the occurrence of problematic behaviors that could reflect any of a number of diagnostic possibilities (see Establishing a Diagnosis for Problematic Drug-Related Behavior). To pursue the most appropriate course, the clinician should establish a working diagnosis and make a judgment about the potential for a future characterized by a favorable balance between the positive outcomes associated with opioid therapy (pain relief and functional gains) and the ongoing risks.

If the decision is made to continue prescribing opioids, a new structure for prescribing should be initiated that is appropriate to the severity of the behaviors demonstrated by the patient. If the problem behavior is relatively minor, e.g., unsanctioned dose escalation once or twice, the change in structure may incorporate relatively little, perhaps more frequent visits and smaller quantities prescribed. If, however, the assessment indicates that the behaviors were serious and the risk of future problems is moderate to high, any of a range of strategies may be implemented. These strategies, which are very similar to those that should be considered proactively at the start of therapy, are designed to increase monitoring and assist the patient in maintaining control over the therapy (see table).

Table: Reactive Strategies That May Be Used to Reduce The Likelihood of Problematic Drug-Related Behaviors and Increase Monitoring (.pdf)

Patients should be taught that the new structure for prescribing is not punitive, but therapeutic. It may be useful to explain that these controls are necessary to allow the clinician to act in the patient's best interest.

If therapy must be restructured, documentation must be comprehensive and complete. The medical record should reflect the thoughtful reassessment and the written plan should be explicit.

The clinician must also decide about the need for referral. If a diagnosis of addiction is tenable, this should be recognized as a serious disease and referral to a specialist in addiction medicine or an addiction program should be strongly considered. Referral to a pain specialist or to a mental health care provider (other than an addiction specialist) should also be considered, where appropriate.

References:

Portenoy RK, Payne R, Passik S: Acute and chronic pain. In Lowinson JH, Ruiz P, Millman RB (eds): Comprehensive Textbook of Substance Abuse, Fourth Edition. Baltimore: Williams and Wilkins, in press.



 

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