Pain and Chemical Dependency News

Predicting opioid misuse by chronic pain patients: a systematic review and literature synthesis

Opioids can provide relief for chronic pain, but a few patients may develop aberrant drug behaviors. Clinicians need to identify those at risk. These researchers examined the evidence for published strategies that identify at-risk patients in order to guide clinicians' decisions and practices for prescribing opioids for chronic pain patients (CPP).

Studies selected screened for predictors of aberrant drug behaviors in CPP who were prescribed long-term opioids. A total of 15 articles and studies were identified. The investigators report that although attempts have been made to use urine toxicology screening, structured interviews, observation, and self-report questionnaires to identify at-risk patients, the designs of questionnaires and interview protocols are weak, and the sample sizes in studies are often small and not representative of the population.

The conclusion is that no one procedure or set of predictors is sufficient to identify CPP at risk for opioid misuse or abuse. There is little evidence regarding characteristics that predict aberrant behavior in patients before they start long-term opioid therapy. Strong predictors identified are a personal history of illicit drug and alcohol abuse. More research with CPP who have not already started chronic opioid therapy is needed. Turk DC, Swanson KS, Gatchel RJ. Adapted from Clin J Pain. 2008 Jul-Aug;24(6):497-508.

PMID: 18574359

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed

Credit: PubMed, developed by the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM).

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Department of Pain Medicine and Palliative Care
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