The aim of this investigation was to study the influence of a central
acting drug, Memantine, in patients with CRPS of one upper extremity.
Six patients were treated with Memantine for 8 weeks; they had developed
CRPS after traumatic injury. Their pain levels were measured using a
numeric pain scale (0=no pain to 10=maximum pain). Motor symptoms were
documented for the fingers and wrist. Before and after pictures were
compared.
The researchers report that six months after treatment with Memantine,
all patients showed a significant decrease in their pain levels and
improvement in motor symptoms and autonomic changes. Based on these
results, the use of Memantine for treatment of CRPS seems promising.
Sinis N; Birbaumer N; Gustin S; Schwarz A; Bredanger S; Becker S; Unertl
K; Schaller H; Haerle M. Adapted from Clin J Pain. 2007 Mar-Apr;23(3):237-43.
PMID: 17314583
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
Credit: PubMed, developed by the National Center for Biotechnology Information
(NCBI) at the National
Library of Medicine (NLM).
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